• NICE recommends daily aspirin for people with Lynch syndrome
    NICE recommends daily aspirin for people with Lynch syndrome

    The recommendation is included in updated draft guidelines on the diagnosis and management of colorectal cancer.

  • Substantial rise in Scottish men undergoing bowel screening
    Substantial rise in Scottish men undergoing bowel screening

    Uptake of screening for bowel cancer has improved significantly since the introduction of FIT.

  • In GI neuroendocrine neoplasms with liver metastasis, primary tumor resection linked to better survival

    Consider PTR in these patients, but factor age and primary tumor site, size, and differentiation into the decision.

  • CRC diagnoses trend younger in the U.S.

    This trend could inform discussions about recommendations for earlier CRC screening.

  • Locally advanced rectal cancer: total neoadjuvant therapy improves response

    A clinical complete response after TNT could trigger a watch-and-wait strategy rather than immediate surgery.

  • Pro-inflammatory diet linked to colorectal cancer risk
    Pro-inflammatory diet linked to colorectal cancer risk

    The association between pro-inflammatory foods and breast cancer was less consistent.

  • Rectal cancer: successful neoadjuvant CRT may obviate need for adjuvant therapy

    Meta-analysis fails to present clear evidence supporting survival benefit.

  • ESMO GI 2019: targeted therapy combination improves survival in colorectal cancer
    ESMO GI 2019: targeted therapy combination improves survival in colorectal cancer

    Data from the phase 3 BEACON CRC study presented at the ESMO World Congress on Gastrointestinal Cancer 2019.

  • ESMO GI 2019: efficacy of flexible regorafenib dosing to relieve side effects
    ESMO GI 2019: efficacy of flexible regorafenib dosing to relieve side effects

    Results of the phase 2 REARRANGE study presented at the ESMO World Congress on Gastrointestinal Cancer 2019.

  • PET/CT could help restage locally advanced rectal cancer

    PET/CT identifies which patients should be considered for operative management.

  • Rectal cancer: Effect of ≥8-week interval between chemo and mesorectal excision

    Meta-analysis of the effect of extending the interval after long-course chemoradiotherapy before surgery in locally advanced rectal cancer

  • Rectal cancer: 4-12-week surgical delay optimal after short-course radiotherapy

    Data from the Stockholm III trial.

  • Cancer risk in women who were breastfed as infants

    Results from a large prospective study of 548,741 women in the UK.

  • Colorectal cancer: managing secondary bowel obstruction

    An analysis of data from the Hospital Episode Statistics over a 10-year period

  • pT1 colorectal cancer: is surgery needed after endoscopic resection?

    Meta-analysis of outcomes with conservatively managed low- and high-risk lesions.

  • Rectal cancer: 5-year survival better with laparoscopic surgery

    Data also show improved recurrence-free survival.

  • Rectal cancer resection: temporary loop ileostomy closure during vs after adjuvant chemotherapy

    Results from a meta-analysis.

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