• Stage IIIC endometrial cancer: chemotherapy first is better than concurrent CRT

    Data show better survival with sequential adjuvant therapy.

  • Nintedanib fails to boost survival in advanced ovarian cancer

    Phase 3 trial shows no benefit with standard frontline chemotherapy.

  • Cervical cancer: psychologic distress tied to higher mortality risk

    Distress within 1 year before or after cancer diagnosis increases mortality.

  • Ovarian cancer: meta-analysis compares primary cytoreduction vs NACT

    NACT tied to lower morbidity, but no survival advantage in advanced disease.

  • NICE approves olaparib maintenance for gynaecological cancers

    Olaparib can be used within the Cancer Drugs Fund for BRCA-positive, advanced epithelial ovarian, fallopian tube or primary peritoneal cancer

  • High-risk endometrial cancer: adjuvant chemoradiotherapy extends survival

    Post hoc analysis of phase 3 PORTEC-3 trial.

  • ESMO-ESGO recommendations for early-stage and borderline ovarian cancer

    Laparotomy for early-stage and fertility-sparing surgery for borderline are recommended.

  • Cervical cancer: paclitaxel-carboplatin-bevacizumab shows efficacy in phase 2

    Objective response rate was 88% in advanced/recurrent disease.

  • Cervical cancer: doubled risk for death with minimally invasive surgery

    Recurrence risk also doubled vs open radical hysterectomy.

  • HPV vaccine could prevent thousands of cancers over the next few decades
    HPV vaccine could prevent thousands of cancers over the next few decades

    Estimates based on a modelling by the University of Warwick.

  • Serum biomarker panel aids early detection of endometrial cancer

    Integrated score of 6 proteins shows AUC of 0.80.

  • Ovarian cancer: adding HIPEC to surgery is cost-effective

    Resulting ICER is within the willingness-to-pay threshold in the Netherlands.

  • Bevacizumab biosimilar gets FDA nod for 5 cancer types

    Bevacizumab-bvzr could offer a cheaper alternative to the reference product.

  • Cytoreductive surgery for ovarian cancer with high tumour burden

    Incorporating cytoreductive surgery into the initial management of epithelial ovarian cancer improves survival

  • Endometrial cancer: benefit of adding radiation to adjuvant chemo in stage III-IVA

    Study identifies which patients are most likely to benefit.

  • HPV vaccination programmes have substantial impact in reducing HPV infections and precancerous cervical lesions
    HPV vaccination programmes have substantial impact in reducing HPV infections and precancerous cervical lesions

    The meta-analysis shows greater and faster impact and herd effects in countries with both multi-cohort and high vaccination coverage.

  • NHS urges women to get cervical cancer screening regardless of their sexual orientation
    NHS urges women to get cervical cancer screening regardless of their sexual orientation

    There is a misbelief that lesbian, gay and bisexual women are not at risk of cervical cancer.

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