Recommended in Gastroenterology

  • Clinical Essentials from PLoS One
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HBV: long-term NA therapy hampers HBeAg seroconversion rates

Entecavir and tenofovir yield lower rates at 3, 4, and 5 y vs spontaneous seroconversion.

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  • Clinical Essentials from PLoS One
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PPI use predicts HF, death in CAD patients

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  • Univadis Medical News
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Trump to appoint vaccine sceptic to chair commission on vaccine safety

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  • Clinical Essentials from Drugs
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HCV-1: 8 wk of LDV/SOF yields high real-world clearance rate

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  • Clinical Essentials
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Glecaprevir/pibrentasvir: 8-wk regimen yields 99% clearance rate in HCV-1

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  • Clinical Essentials from Inflamm Bowel Dis
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IBD: 1 in 5 patients has coexisting IBS

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  • Univadis Medical News
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Diarrhoea vaccine saves £12.5 million in UK healthcare costs

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  • Gastroenterology
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HCV infection in hepatocytes: SMAD6 and SMAD7 regulates HSPG expression and HCV entry

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  • Clinical Essentials from J. Clin. Oncol
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HCC: is sorafenib more effective in HCV+ patients?

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Professional & Business

  • International Medical Press

Think-tank calls for rethink over obesity impact

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  • International Medical Press

E-cigarettes cause teen nicotine addiction, says study

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  • International Medical Press

Unfilled nurse shifts compromising patient safety

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  • International Medical Press

‘Biggest leap forward’ in prostate cancer diagnosis

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  • International Medical Press

Vaccines fast-tracked to prevent global epidemics

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  • International Medical Press

Yorkshire CCGs place ban on expensive treatments

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New in Gastroenterology

  • Clinical Essentials from Amyotroph Lateral Scler Frontotemporal Degener
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PEG placement in ALS: new risk-stratifying tool developed

A new risk-stratifying tool can help guide modifications of PEG placement in patients with advanced ALS.

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Link between debt and death
  • Univadis Medical News
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Link between debt and death

The finding could have significant implications for healthcare policy.

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  • Clinical Essentials from Am J Gastroenterol
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IBS is underdiagnosed and undertreated in the US

Up to 48 million Americans are thought to be affected by IBS.

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  • Clinical Essentials from Nutrients
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Drinking coffee lowers liver stiffness in HCV, HBV, and NAFLD

Could drinking 2 or more cups of coffee daily have a hepatoprotective effect?

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Concerns voiced after first baby is born using pronuclear transfer
  • Univadis Medical News
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Concerns voiced after first baby is born using pronuclear transfer

The infant has the genetic make-up of his parents combined with a small amount of mitochondrial DNA from a donor.

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  • Clinical Essentials from Lancet Gastroenterol Hepatol
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IBD: do psychological therapies improve outcomes?

A meta-analysis of 14 studies.

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  • Clinical Essentials from Biomed Pharmacother
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Antidepressants to treat cancer? SSRIs show oncolytic and chemosensitizing effects

A review of published evidence suggests that SSRIs combat more than cancer-related depression.

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  • Clinical Essentials from Aliment Pharmacol Ther
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HCV-3: prescribers quick to adopt new treatment regimens

Real-world data show rapid evolution of therapeutic strategies during 20-mo period.

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OECD report criticises pharmaceutical pricing strategies
  • Univadis Medical News
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OECD report criticises pharmaceutical pricing strategies

Payers must be able to lower or withdraw payment for new therapies that do not live up to expectations in the real world, according to the OECD.

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  • Clinical Essentials from PLoS One
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Barrett's esophagus: do PPIs reduce esophageal cancer risk?

Results of a meta-analysis.

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  • Clinical Essentials from Clin Res Hepatol Gastroenterol
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SOF+DCV highly effective for HCV-1 and HCV-3 in LT recipients

Meta-analysis suggests efficacy may be hampered by add-on RBV.

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  • Clinical Essentials from J Community Med Health Educ
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Survey: PCPs remain unwilling to treat HCV in the DAA era

Although the majority was aware of DAAs, few agreed that they should be offered in primary care.

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  • Clinical Essentials from J Am Coll Cardiol
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What is behind “aspirin resistance” in type 2 diabetes?

Enteric-coated aspirin is associated with a lower antiplatelet response as a result of impaired gastrointestinal absorption.

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  • Clinical Essentials from Hepatol Int
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Post-LT HCV-1: LDV/SOF highly effective without RBV

Current guidelines recommend add-on ribavirin, but its value remains controversial.

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