Recommended in Infectious Diseases

  • Clinical Essentials from JAMA
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New sepsis, septic shock guidelines released

Updated recommendations highlight need for antibiotic stewardship, more dynamic intervention.

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  • Clinical summaries
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Zinc lozenges may shorten common cold by 3 d

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  • Clinical Essentials from Vaccine
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Influenza vaccination rates low in elderly diabetics, household contacts

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  • Clinical Essentials from http://bmcpediatr.biomedcentral.com/articles/10.1186/s12887-017-0776-1
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HIV-infected infants require early ART to optimize cognitive outcomes

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  • Clinical Essentials from JAMA Oncol
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NHANES: genital HPV affects 45% of US men

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  • Clinical Essentials from N Engl J Med
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Transmission implicated for rapid expansion of extremely drug-resistant TB

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  • Clinical Essentials from Lancet Respir Med
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Severe influenza: is intravenous zanamivir an option for hospitalized patients?

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  • Univadis Medical News
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Concerns voiced after first baby is born using pronuclear transfer

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  • Univadis Editorial - Dr Harry Brown
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The nightmare that is meningitis

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Professional & Business

  • International Medical Press

Vaccines fast-tracked to prevent global epidemics

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  • International Medical Press

Yorkshire CCGs place ban on expensive treatments

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  • International Medical Press

Forecasts suggest NHS will need extra £88bn by 2067

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  • International Medical Press

Addenbrooke’s hospital comes out of special measures

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  • International Medical Press

BMA accuses PM of ‘scapegoating’ GPs for NHS crisis

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  • International Medical Press

Half of women face red flag event during childbirth

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New in Infectious Diseases

  • Clinical Essentials from Nutrients
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Drinking coffee lowers liver stiffness in HCV, HBV, and NAFLD

Could drinking 2 or more cups of coffee daily have a hepatoprotective effect?

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  • Clinical Essentials from MMWR Morb Mortal Wkly Rep
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West Nile Virus: include in differentials for aseptic meningitis, encephalitis

West Nile Virus continues to pose a challenge to diagnosis, management of severe neuroinvasive arboviral diseases.

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Emerging Infectious Disease: Monthly Essentials January 2017
  • Monthly Essentials
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Emerging Infectious Disease: Monthly Essentials January 2017

Ebola vaccine | Zika persists in brain, placenta | 6% risk for Zika birth defects.

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  • Clinical Essentials from CMAJ
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Bacterial pneumonia: is there added diagnostic value to measuring CRP?

Routine bacterial testing for all patients who present with acute cough is not feasible in primary care, making better markers of bacterial causes important.

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Healthcare-associated infections affect 1 in 6 children in paediatric intensive care units
  • Univadis Medical News
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Healthcare-associated infections affect 1 in 6 children in paediatric intensive care units

Bloodstream infections were the most common healthcare-associated infections in children in Europe.

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OECD report criticises pharmaceutical pricing strategies
  • Univadis Medical News
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OECD report criticises pharmaceutical pricing strategies

Payers must be able to lower or withdraw payment for new therapies that do not live up to expectations in the real world, according to the OECD.

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  • Clinical Essentials from The Journal of the American Board of Family Medicine
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Scabies frequently misdiagnosed

WHO has declared scabies a neglected skin disease.

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  • Clinical Essentials from Aliment Pharmacol Ther
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HCV-3: prescribers quick to adopt new treatment regimens

Real-world data show rapid evolution of therapeutic strategies during 20-mo period.

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  • Clinical Essentials from Eur Heart J
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Infective endocarditis up to 44 times more likely in ACHD

Valve-containing prosthetics, multiple cardiac lesions, history of IE, and male sex all increased risk for infection.

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  • Clinical Essentials from AIDS Res Hum Retroviruses
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HIV lipohypertrophy and lipoatrophy: distinct clinical entities with different risk factors

Lipohypertrophy and lipoatrophy remain common in patients with HIV..

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  • Clinical Essentials from CMAJ
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Pneumonia: meta-analysis suggests adding C-reactive protein measurement

Previous meta-analyses suffered from heterogeneity, using different combinations of signs and symptoms with CRP measurement.

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  • Clinical Essentials from JAMA
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Sepsis: qSOFA >2 most prognostic for in-hospital mortality

Rely on quick Sequential Organ Failure Assessment (qSOFA) scores to accurately manage potential severe outcomes in patients presenting to ED with infection.

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  • Clinical Essentials from Lancet
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Enhanced disinfection strategies recommended to reduce multidrug resistance during hospital admission

Addition of UV-C during admission/discharge may reduce multidrug resistance rates.

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  • Clinical Essentials from PNAS
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Carbapenem-resistant enterobacteriacae more widespread than believed

New report shows significant diversity, asymptomatic transmission in carbapenem-resistant enterobacteriacae.

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