ONCOLOGY

It is the first adjuvant therapy to show a benefit over placebo in this population.

Chemotherapy is associated with less than a year survival and significant toxicity.

Efficacy of NAC with standard surgery was already established.

Laparoscopic total gastrectomy already has been widely adopted.

Results support current recommendations of polychemotherapy, ramucirumab plus chemotherapy.

Royal Marsden study finds that microscopic colitis is an important subgroup in patients with immune checkpoint inhibitor-related diarrhoea/colitis.

Findings could help prioritize surgical procedures amidst the COVID-19 pandemic.

Trial included patients with HER2+ LA/mGC in the phase 1 component.

Many advanced gastric cancers are resistant or unresponsive to anti-PD-1 therapies.

Existing third-line therapies have limited benefit in this population.

A case-control study within the Scottish Primary Care Clinical Informatics Unit database and a cohort study from the UK Biobank.

Findings in matched analysis strengthen confidence in observational results.

Meta-analysis of observational studies confirms the association.

Results from a meta-analysis of 10 randomised controlled trials.