ONCOLOGY

By activating the bacterial SOS response, chemotherapy treatments promote antibiotic resistance and bacterial translocation.

PIK3CA mutation status predicted resistance to cetuximab.

Phase 2 trial shows efficacy regardless of high-risk HPV type.

Data from the phase 2 pembrolizumab KEYNOTE-158 basket study.

HIV coinfection increases HPV-related cancer risk.

Meta-analysis supports noninferiority in para-aortic node detection, recurrence.

Phase 2 QUADRA shows benefit extends to HRD-positive platinum-sensitive disease.

Indocyanine green identifies 26% more SLN than methylene blue dye.

Combination received FDA breakthrough therapy designation.

Phase 3 data support similar efficacy vs doxorubicin plus cisplatin.

The study was carried out by the Cancer Research UK Institute at the University of Manchester.

Reductions in mortality driven by lung cancer in men, breast cancer in women.

The campaign aims to improve uptake by encouraging women to attend screening.

National implementation of minimally invasive robotic surgery changes surgical approach.