Recommended in Pharmacists

EMA recommends suspension of several medicines due to unreliable study data
  • Univadis Medical News
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EMA recommends suspension of several medicines due to unreliable study data

The European Medicines Agency inspection team identified a number of concerns, including misrepresentation of study data.

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  • Clinical summaries
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Can vitamin C supplementation improve glycaemic control? Meta-analysis

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  • Univadis Medical News
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Trump's proposed healthcare Bill pulled at 11th hour

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  • Clinical summaries
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  • FULLTEXT

New consensus statement on inhaled treatment of COPD

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  • Clinical summaries
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Improvement in statin adherence of 20% lowers risk for stroke by 8%

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  • BMJ News
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GPs found wanting on women’s health

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  • Clinical Essentials from Cancer
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AML: treosulfan-based conditioning improves survival outcomes, reduces toxicity

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  • Clinical Essentials from Arab J Gastroenterol
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HCV: DAAs linked to reports of herpes reactivation

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  • Clinical Essentials from FDA
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FDA approves avelumab for metastatic Merkel cell carcinoma

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Professional & Business

  • International Medical Press

Half of £2bn cash boost spent outside NHS

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  • International Medical Press

Report: GPs not treating gynaecological patients ‘with dignity or respect’

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  • International Medical Press

Bariatric surgery rationing ‘misguided’

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  • International Medical Press

Scottish NHS increases access to IVF treatment

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  • International Medical Press

£2bn for social care ‘not solution to the crisis’

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  • International Medical Press

Less than half of women breastfeed after 2 months

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New in Pharmacists

Asthma and COPD: Monthly Essentials March 2017
  • Monthly Essentials
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Asthma and COPD: Monthly Essentials March 2017

LAMA+LABA for COPD | No link between inhaled corticosteroids, pneumonia in pediatric asthma | Aclidinium/formoterol safe, effective for COPD.

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  • Clinical Essentials from Aliment Pharmacol Ther
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Eluxadoline for IBS-D: early response predicts long-term effect

A post-hoc analysis of two phase 3 studies.

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  • Clinical Essentials from BMC Neurol
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Interferon-β-1a for MS: predictors of discontinuation identified

Data from a cohort study of over 5900 patients.

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Weaponisation of health care in Syria
  • The Lancet
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  • FULLTEXT

Weaponisation of health care in Syria

A strategy of using violence to restrict or deny access to health care as a weapon of war

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  • Clinical Essentials from Breast Cancer
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Advanced HR+ breast cancer: adding targeted agents to fulvestrant boosts PFS

Results of a meta-analysis.

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  • Clinical Essentials from Cancer
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High-risk prostate cancer: docetaxel, ADT add benefit to adjuvant radiation

Data from the RTOG 0621 study.

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  • Clinical Essentials from Diabetes Care
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Type 2 diabetes: what's the best way to intensify therapy in patients already on insulin?

Meta-analysis suggests adding a GLP-1RA to basal insulin is a promising option.

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  • Clinical Essentials from Hepatol Res
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HCV: EBR/GZR safe, effective in moderate renal impairment

eGFR remained stable or improved in patients treated for 8-18 wk.

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  • Clinical Essentials from Cochrane Database Syst Rev
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Cochrane review: probiotic diet may be beneficial for recurrent pediatric abdominal pain

Fiber supplements and other dietary interventions show only weak evidence of improvement.

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  • Clinical Essentials from PLoS One
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Meta-analysis: adenosine curbs post-op pain, but not opioid use

Adenosine most beneficial for patients with high systolic BP.

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  • Clinical Essentials from Breast Cancer Res Treat
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Breast cancer: ridaforolimus + dalotuzumab no better, more toxic than exemestane

International phase 2 study ended prematurely due to lack of efficacy and adverse events.

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  • Clinical Essentials from J Am Assoc Nurse Pract
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HPV: how common is vaccination among lesbian and bisexual women?

Study contradicts prior data suggesting lower uptake vs heterosexual women.

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  • Clinical Essentials from PLoS One
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HIV: drug resistance rate tops 19% among newly diagnosed MSM in LA

Transmitted drug resistance to HIV is estimated as high as 12%-24%.

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  • Clinical Essentials from Patient Prefer Adherence
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Adherence to MS therapy: belief in disease etiology plays a role

Patients believing in a supernatural etiology were less likely to adhere to DMTs.

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