Most read in Pharmacists

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Does timing of statin intake matter?

Cochrane review of chronotherapy vs conventional treatment with statins.

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Acid suppressants may raise intestine risk

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Can cardiac troponin response predict CHD risk related to statin?

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Heavy menstrual bleeding: what works best in the long term?

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  • BMJ News
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Mouthwash may reduce gonorrhoea

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How much vitamin D is beneficial for the elderly? | UK study

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  • Univadis Medical News
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Doctor's near-death experience inspires campaign to improve doctors' patient communication skills

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How much lipid lowering on statins calls for diabetes attention?

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  • Clinical Essentials from Obesity (Silver Spring)
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Weight loss: real-world data support naltrexone-bupropion efficacy

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Professional & Business

  • International Medical Press

Review raises concerns over locum doctors

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Hospitals braced for cold weather ‘spike’

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Hospitals declare ‘black alert’ due to overcrowding

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  • International Medical Press

Former GMC chief to lead NHS Confederation

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NHS warning from leading doctors and nurses

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Plans for seven-day GPs ‘in disarray’

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New in Pharmacists

Uni drive doubles meningitis vaccine rate
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Uni drive doubles meningitis vaccine rate

A campaign asking freshers arriving at university whether they had been vaccinated against meningitis and offering free vaccination to unvaccinated students...

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Aspirin for frequent tension headache queried
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Aspirin for frequent tension headache queried

Evidence of aspirin’s efficacy for relieving acute pain in people with frequent episodic tension-type headache is limited, a Cochrane review of randomised...

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Fresh Brexit concerns for European doctors
  • Univadis Medical News
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Fresh Brexit concerns for European doctors

Organisations representing doctors have warned Brexit must not be permitted to threaten Europe’s health.

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Antidepressants double the risk of hip fracture in patients with Alzheimer’s disease
  • Univadis Medical News
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Antidepressants double the risk of hip fracture in patients with Alzheimer’s disease

The increased fracture risk seen with antidepressant use in older people appears to be even greater in patients with Alzheimer’s disease.

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  • Clinical Essentials from Pediatrics
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PICC lines needed on pneumonia discharge? Expert comment

Jonathan Temte, MD, PhD, comments on a recent trial on oral vs PICC antibiotics on hospital discharge for pediatric pneumonia.

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  • Clinical Essentials from Acta Oncol
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MCRPC: low NLR linked to improved survival with docetaxel

Neutrophil-to-lymphocyte ratio ≤3 was associated with a mean benefit in OS of almost 15 mo.

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Dementia: Monthly Essentials January 2017
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Dementia: Monthly Essentials January 2017

3 meta-analyses: Benzodiazepines and Dementia | Albuminuria and Dementia | Antidepressants and Dementia

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  • Clinical Essentials from Eur Heart J
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ACS: patients with HIV have higher platelet reactivity in response to dual antiplatelet therapy

HIV-infected individuals are at higher risk for ischemic events.

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  • Clinical Essentials from Aliment Pharmacol Ther
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IBD: vitamin D levels influence response to anti-TNFs

Vitamin D has been linked to disease activity and duration of anti-TNF therapy in patients with IBD.

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  • Clinical Essentials from Cochrane Database Syst Rev
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Asthma: Cochrane review finds better outcomes with combined inhaled therapy in the ED

Benefits appear to be independent of co-treatment with corticosteroids.

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OECD critical of 'wasteful clinical care’ in new report
  • Univadis Medical News
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OECD critical of 'wasteful clinical care’ in new report

According to the OECD, more than 10 per cent of hospital expenditure is spent on correcting preventable medical mistakes or infections.

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  • Clinical Essentials from PLoS One
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HCV-4: can first-line simeprevir-PR be shortened to 12 wk?

Small phase 3 study shows 97% clearance rate in early responders with mild-moderate fibrosis.

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  • Clinical Essentials from Medicine (Baltimore)
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Head/neck mucosal melanoma: study supports adjuvant radiation for primary tumors

Adjuvant radiation of the primary tumor reduces recurrence risk, and PD-1 inhibitors improve survival in metastatic disease.

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  • Clinical Essentials from BMC Cancer
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NSCLC with brain metastases: adding temozolomide to WBRT boosts outcomes

Adding temozolamide to WBRT improved ORR, DCR, and PFS.

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