Recommended in Pharmacists

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Is ibuprofen good enough to prevent high altitude headache?

Results from a meta-analysis.

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  • Univadis Medical News
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NICE approves ustekinumab for treating Crohn’s disease

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  • Clinical Essentials from Aliment Pharmacol Ther
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DAAs for HCV: no evidence of HBV reactivation with resolved infection

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  • Clinical Essentials from Eur Urol
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Urological cancers: where do checkpoint inhibitors fit in the treatment paradigm?

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  • Clinical Essentials from Leukemia
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Phase 3 results for darbepoetin alfa in lower-risk MDS with anemia

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  • Clinical Essentials from JAMA Oncol
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PPI+capecitabine: worse outcomes in gastroesophageal cancer

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  • Clinical Essentials from N Engl J Med
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Recombinant influenza vaccine offers better protection for seniors

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  • Clinical Essentials from Cochrane Database Syst Rev
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Cochrane review: umeclidinium in COPD

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  • The Lancet
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Unbiased, credible data on violence against health care in Syria

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Professional & Business

  • International Medical Press

Call for improved GP resources as postnatal depression missed

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  • International Medical Press

BMA: government fails to acknowledge NHS ‘at breaking point’

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  • International Medical Press

RCOG outlines steps to prevent baby deaths and injuries during birth

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  • International Medical Press

Study clarifies cancer risk for BRCA gene mutations

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  • International Medical Press

Medicine information leaflets too complex, say experts

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  • International Medical Press

NHS appeal for more black people to give blood

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New in Pharmacists

Stroke: Monthly Essentials June 2017
  • Monthly Essentials
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Stroke: Monthly Essentials June 2017

Hospital admission for TIA? | Predicting long-term stroke outcomes | Delayed treatment for minor stroke.

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  • Clinical Essentials from Int J Drug Policy
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HCV treatment tied to reduced substance abuse among PWID

Results of the international ACTIVATE trial.

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  • Clinical Essentials from Hepatology
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HBV: HCC risk drops after 5 y on entecavir/tenofovir

Data from a large, multicenter, ongoing cohort study.

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  • Clinical Essentials from Breast
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Metastatic breast cancer: CDK4/6 inhibitors are well-tolerated

Results of a meta-analysis of palbociclib and ribociclib.

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  • Clinical Essentials from JAMA Oncol
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NSCLC: delayed adjuvant chemotherapy shows benefit

Adjuvant chemotherapy is effective even when started 7-18 wk post-resection.

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  • Conference reports - RSi Communications
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Eculizumab improves pregnancy outcomes in patients with PNH | EHA

Clinical manifestations of hemolysis significantly regressed during eculizumab treatment.

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Only 16% of patients with asthma completely adherent | EAACI
  • Conference reports - RSi Communications
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Only 16% of patients with asthma completely adherent | EAACI

Study highlights need for stronger belief that benefits outweigh potential harm.

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  • Clinical Essentials from Ann Oncol
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R/R lymphoma: phase 2 results for copanlisib in aggressive and indolent disease

Meaningful responses in heavily pretreated patients.

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  • Clinical Essentials from Invest New Drugs
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ES-SCLC: amrubicin is a viable treatment option for certain patients

Phase 2 data show benefit in chemotherapy-naive elderly, poor-risk patients.

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  • Clinical Essentials from Circulation
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Lower BP targets may yield CV benefits in high-risk patients

Study involving over 31K patients supports BP target below 140/90 mmHg,

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Medicine information leaflets ‘impenetrable’ and ‘unreadable’
  • Univadis Medical News
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Medicine information leaflets ‘impenetrable’ and ‘unreadable’

A new report calls for major changes to medicine patient information leaflets.

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Single-gene mutations that lead to atopic dermatitis identified
  • Univadis Medical News
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Single-gene mutations that lead to atopic dermatitis identified

The findings suggest some the genetic defects underpinning atopic dermatitis could be corrected by glutamine supplementation.

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Obesity could blunt the efficacy of influenza vaccine
  • Univadis Medical News
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Obesity could blunt the efficacy of influenza vaccine

Alternative vaccination approaches needed for obese individuals.

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  • Clinical Essentials from Ann Oncol
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MCRC: less hand-foot syndrome with S-1 vs capecitabine

Data from the phase 3 SALTO trial show reduced incidence, severity.

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