Recommended in Pharmacists

  • Clinical summaries
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Are e-cigarettes encouraging young Britons to smoke?

First study to report longitudinal association.

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  • Univadis Medical News
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Patients with depression likely to have lower folate levels

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  • Clinical Essentials from Lancet
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GLE/PIB yields 99% clearance rate in HCV with compensated cirrhosis

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  • Clinical Essentials from J. Viral Hepat
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HCV-1b with cirrhosis: extending LDV/SOF duration tops adding RBV

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  • Clinical Essentials from Leukemia
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CML: patient, disease factors outweigh first-line treatment type

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  • Clinical Essentials from FDA
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FDA approves olaparib maintenance therapy for ovarian cancer

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  • Clinical summaries
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Statins prescribing pattern in the UK

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  • Clinical summaries
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NICE issues recommendations on bisphosphonates for treating osteoporosis

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  • Clinical Essentials from Ann Intern Med
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HCV: DAA cure rates equally high with nonspecialists

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Professional & Business

  • International Medical Press

Calorie reduction next step in childhood obesity plan

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  • International Medical Press

Third of trainee GPs plan to leave NHS within 6 months

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  • International Medical Press

Proposed cuts to sexual health services deemed ‘unsafe’

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  • International Medical Press

Government to cover rising GP indemnity fees

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  • International Medical Press

Type 2 diabetes in children on the rise

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  • International Medical Press

UKSTSG training report gets mixed response

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New in Pharmacists

  • Clinical Essentials from J Clin Oncol
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Breast cancer: 70-gene test changes 51% of chemo decisions

A low 70-gene signature score means chemotherapy is avoidable.

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  • Clinical Essentials from Eur J Cancer
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Breast cancer brain mets: capecitabine adds survival benefit to lapatinib

Meta-analysis suggests combination therapy should be considered a first-line option.

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  • Clinical Essentials from J Clin Oncol
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Extensive stage SCLC: palifosfamide fails phase 3 MATISSE trial

Adding palifosfamide to carboplatin and etoposide failed to improve survival.

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  • Clinical Essentials from J Pain Res
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Caffeine with opioids effective in fibromyalgia

A little caffeine may help manage pain.

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  • Clinical Essentials from Pediatrics
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AAP issues new guidelines for pediatric hypertension

First-line treatment remains the same: lifestyle changes.

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  • Clinical Essentials from Endocr Pract
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What’s the best treatment intensification strategy in type 2 diabetes?

Not all patients achieve recommended HbA1c levels even after adequate basal insulin titration.

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  • Clinical Essentials from PLoS One
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Fasting blood glucose test may miss diabetes diagnosis

Significant discordance in diabetes diagnosis rates seen between FPG and HbA1c measurements.

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Blood donation criteria in England revised
  • Univadis Medical News
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Blood donation criteria in England revised

Decision will enable more people to donate blood.

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  • Clinical Essentials from J Natl Compr Canc Netw
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Breast cancer: extended tamoxifen tops ovarian ablation/AI therapy

Lifetime outcomes are better, and costs lower, with continued tamoxifen.

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  • Clinical Essentials from Ann Surg Oncol
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HPV+ OPSCC: adjuvant therapy reduces recurrence risk

Adjuvant therapy improves outcomes after transoral resection.

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  • Clinical Essentials from Eur Neurol
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Parkinson's disease: meta-analysis confirms efficacy of adjuvant entecapone

Adding entecapone to levodopa reduces motor fluctuation in later disease.

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Heart Disease: Monthly Essentials August 2017
  • Monthly Essentials
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Heart Disease: Monthly Essentials August 2017

Embolic protection devices not so protective | The most effective HFpEF drugs | Aspirin, HF, and some Nietzsche.

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  • Clinical Essentials from J Clin Oncol
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MCRPC: low-dose cabazitaxel is safer alternative in second-line setting

PROSELICA trial compared 20 and 25 mg/m2 dosing regimens

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  • Clinical Essentials from JAMA
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Does intensive lifestyle intervention enhance standard care in recent-onset type 2 diabetes?

Some possible benefit for some patients in the first decade after diagnosis.

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