Recommended in Thoracic Medicine

  • Clinical summaries
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NICE recommends treatment options for multiple myeloma and NSCLC

Appraisal guidances for pomalidomide and pembrolizumab.

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Statin use in acute respiratory distress syndrome questioned

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  • Univadis Medical News
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Higher obesity risk for children with asthma

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  • Clinical Essentials from Ann Card Anaesth
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H1N1 pneumonia: does ECMO help in acute respiratory failure?

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  • Clinical Essentials from J Clin Sleep Med
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Sleep: at-home tests may underestimate OSA

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  • Clinical Essentials from Am J Respir Crit Care Med
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COPD: women smokers more vulnerable than men

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  • Univadis Medical News
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Trump to appoint vaccine sceptic to chair commission on vaccine safety

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  • Clinical Essentials from J Oral Rehabil
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OSA: mandibular advancement devices may carry risks

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  • Clinical Essentials from Thorax
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Usual interstitial pneumonia: can nondefinitive CT scans replace lung biopsy?

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Professional & Business

  • International Medical Press

Think-tank calls for rethink over obesity impact

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  • International Medical Press

E-cigarettes cause teen nicotine addiction, says study

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  • International Medical Press

Unfilled nurse shifts compromising patient safety

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  • International Medical Press

‘Biggest leap forward’ in prostate cancer diagnosis

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  • International Medical Press

Vaccines fast-tracked to prevent global epidemics

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  • International Medical Press

Yorkshire CCGs place ban on expensive treatments

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New in Thoracic Medicine

  • Clinical Essentials from Clin Exp Metastasis
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NSCLC: new model may help predict onset of brain metastases

Model based on MRI data may reliably predict brain metastases in 6 mo or 1 y.

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  • Clinical Essentials from Int J Chron Obstruct Pulmon Dis
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COPD: indacaterol tops all other LABA monotherapies

A systematic review of 33 randomized controlled trials.

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  • Clinical Essentials from Chin J Cancer
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NSCLC: mismatch repair polymorphisms may predict chemotoxicity

MMR polymorphisms show potential as markers for toxicity with platinum-based chemotherapy.

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  • Clinical Essentials from Ann Thorac Surg
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NCLC: outcomes similar with robotic lobectomy vs open surgery, VATS

Use of robotic lobectomies has significantly increased in stage I to IIIA NSCLC.

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  • Clinical Essentials from Am J Respir Crit Care Med
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Pediatric asthma raises obesity risk

Early intervention may prevent a vicious cycle of worsening obesity and asthma.

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  • Clinical Essentials from Amyotroph Lateral Scler Frontotemporal Degener
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PEG placement in ALS: new risk-stratifying tool developed

A new risk-stratifying tool can help guide modifications of PEG placement in patients with advanced ALS.

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Link between debt and death
  • Univadis Medical News
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Link between debt and death

The finding could have significant implications for healthcare policy.

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  • Clinical Essentials from J Allergy Clin Immunol
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Chronic cough: can FeNO diagnose cough-variant asthma, eosinophilic bronchitis?

If accurate, the test would offer a simple and rapid alternative to current diagnostic methods.

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Efficacy and safety of simtuzumab in patients with idiopathic pulmonary fibrosis
  • The Lancet Pneumology
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Efficacy and safety of simtuzumab in patients with idiopathic pulmonary fibrosis

Phase 2 trial of simtuzumab vs placebo.

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  • Clinical Essentials from J Clin Oncol
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Advanced NSCLC: major treatment shifts have yielded only modest survival benefit

Findings highlight the need to weigh treatment benefit against cost.

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  • Clinical Essentials from N Engl J Med
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Transmission implicated for rapid expansion of extremely drug-resistant TB

Transmission, rather than inadequate TB treatment, likely responsible for rapid spread of XDR TB.

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A third of community-diagnosed asthmatics do not have asthma
  • Univadis Medical News
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A third of community-diagnosed asthmatics do not have asthma

Potentially serious conditions were misdiagnosed as asthma in 2 per cent of participants.

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  • Clinical Essentials from J Allergy Clin Immunol Pract
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Asthma: spacers do not reduce risk for severe exacerbations, oral thrush

The findings of this large cohort study challenge long-held assumptions that spacers improve pMDI effectiveness.

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Concerns voiced after first baby is born using pronuclear transfer
  • Univadis Medical News
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Concerns voiced after first baby is born using pronuclear transfer

The infant has the genetic make-up of his parents combined with a small amount of mitochondrial DNA from a donor.

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