ANTIBIOTICS

An unexpected benefit of prudent antibiotic use.

A strong dose-response was found between the patterns of changes in hospitalisation risk and level of prior antibiotic use

A large proportion of Salmonella bacteria are multidrug-resistant, the report found

Macrolide prescribing in any trimester was associated with an increased risk of genital malformations

Study shows utility of deep learning approaches to expand antibiotic arsenal through the discovery of structurally distinct antibacterial molecules

Further spread of CPE is an increasing threat to public health and medical treatment pathways in the UK, according to PHE

The study examined whether repeated antibiotic exposure by age 48 months is associated with higher BMI at age 54 months

The drink has potential to work against bacteria including E. coli, Salmonella, and Klebsiella pneumoniae

The findings offer new insights into the determinants of plasmid mobility and have implications for the development of targeted treatments

The document covers the use of ceftolozane with tazobactam for treating hospital-acquired pneumonia, including ventilator-associated pneumonia

Of the antibiotic agents in the pipeline, only a few target rapidly spreading, multi-drug resistant Gram-negative bacteria

Only 19% of patients with suspected sepsis received antibiotics in the first hour; worse than previous audits

The results suggest the need to consider drug tolerance when designing antibiotic treatments to prevent antibiotic-resistant pathogens

The results highlight the need for evidence-based guidance to help improve clinical and efficiency outcomes in critical care