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Point-of-care CRP testing of febrile patients in primary care reduces antibiotic prescriptions - study Point-of-care tests for host-response biomarkers offer an alternative to pathogen-specific testing, and potential for ruling out antibiotic treatment
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PHE issues testing and treatment guidance on multi-drug resistant Shigella sonnei cluster Guidance issued for assessing the susceptibility of Shigella sonnei isolates, in response to PHE investigation of a multi-drug resistant cluster
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Altered wasp venom peptides show promise as a novel antimicrobial agent Antimicrobial peptides are a promising alternative to conventional antibiotics because of their potency against difficult-to-treat infections
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Cases of MRSA stable, C.difficile down, while MSSA continues to rise; latest English data shows The incidence rate of all reported E. coli bacteraemia has also continued to increase
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New US guidelines for management of outpatient parenteral antimicrobial therapy (OPAT) The guidelines cover various patient features, infusion catheter issues, monitoring questions, and antimicrobial stewardship concerns
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Invasive infant group B streptococcal disease rises in the UK despite antibiotic prophylaxis guidelines Of the 27 infants with early-onset disease who died during study period, only one had received intrapartum antibiotic prophylaxis
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Public Health England publishes new antimicrobial prescribing resources for healthcare professionals New PHE data shows that antibiotic-resistant bloodstream infections rose by an estimated 35% between 2013 and 2017
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Call for increased resources and political will to tackle antimicrobial resistance in Europe Study released ahead of European Antibiotic Awareness Day estimates that 33,110 deaths annually in EU/EEA are attributable to antibiotic-resistant infections
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NICE issues four new antibiotic guidance documents The guidance documents cover antibiotic prescribing for UTIs, acute pyelonephritis, and acute prostatitis
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New investigational antibiotic effective against multidrug-resistant bacteria in phase 2 trial Cefiderocol has broad in-vitro activity against Gram-negative pathogens, including multidrug-resistant and carbapenem-resistant strains.
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£32 million competition launched for antimicrobial resistance research Prof Dame Sally Davies said that this substantial capital funding will be a significant step towards strengthening UK-based AMR initiatives.
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Significant decrease in UK case fatality rates of major healthcare-associated infections in last decade The greatest number of deaths is seen following E. coli bacteraemia due to its higher incidence
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Ciprofloxacin found to have dramatic negative effects on the mitochondrial genome and should thus be used with caution - study The study provides novel insights into the mitochondrial effects of broad-spectrum antibacterial antibiotics fluoroquinolones.
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Inappropriate antibiotic prescribing widespread in outpatient setting - study of over 500K prescriptions finds In the study, 29% of antibiotic prescriptions were for non-infection-related conditions and 17% were associated with no diagnosis.
ANTIBIOTICS
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