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NICE issues four new antibiotic guidance documents The guidance documents cover antibiotic prescribing for UTIs, acute pyelonephritis, and acute prostatitis
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New investigational antibiotic effective against multidrug-resistant bacteria in phase 2 trial Cefiderocol has broad in-vitro activity against Gram-negative pathogens, including multidrug-resistant and carbapenem-resistant strains.
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£32 million competition launched for antimicrobial resistance research Prof Dame Sally Davies said that this substantial capital funding will be a significant step towards strengthening UK-based AMR initiatives.
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Significant decrease in UK case fatality rates of major healthcare-associated infections in last decade The greatest number of deaths is seen following E. coli bacteraemia due to its higher incidence
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Ciprofloxacin found to have dramatic negative effects on the mitochondrial genome and should thus be used with caution - study The study provides novel insights into the mitochondrial effects of broad-spectrum antibacterial antibiotics fluoroquinolones.
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Inappropriate antibiotic prescribing widespread in outpatient setting - study of over 500K prescriptions finds In the study, 29% of antibiotic prescriptions were for non-infection-related conditions and 17% were associated with no diagnosis.
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IDWeek 2018 — Efficacy and safety data for newly FDA-approved omadacycline Results from OPTIC and OASIS 1 and 2 trials.
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IDWeek 2018 — A look at the antibiotics pipeline Session focused on near-clinic antibiotics, including novel therapies.
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IDWeek 2018 — Novel combination therapy for cUTI: PLEA trial results Safety and efficacy results for this "novel antibiotic adjuvant entity."
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IDWeek 2018 — Battling resistant Enterobacteriaceae and other Gram-negative pathogens Emerging effectiveness of a new agent in UTI, other conditions.
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IDWeek 2018 — Using a DOOR-MAT to gauge appropriate antibiotic therapy in BSI Framework allows tracking effectiveness of RMD-guided therapy
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IDWeek 2018 — Is fecal microbial transplant going to save modern medicine? Hints that FMT reduces antibiotic use and resistance.
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IDWeek 2018 — Asymptomatic bacteriuria: a guidelines update Update focuses on previously overlooked populations.
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IDWeek 2018 — Practice-changing antimicrobial RCTs Some old agents offer new strategies.