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Latest drug updates

  • 8 Nov 2017 - Drug Updates

Gabapentin (Neurontin): Risk of developing respiratory depression without concomitant use of opioids

Advise patients on gabapentin to seek medical help if they experience any trouble breathing or are taking shallow breaths.

  • 31 Jul 2017 - Drug Updates

Daclizumab (Zinbryta▼) in multiple sclerosis: Review patients for liver function currently on treatment

Initiate daclizumab in restricted groups of patients with limited treatment options and closely monitor liver function.

  • 28 Apr 2017 - Drug Updates

Valproate (Epilim▼, Depakote▼): High risk of neurodevelopmental disability and birth defects

Valproate should not be prescribed to women and girls of childbearing potential unless other treatments are ineffective or not tolerated.

  • 28 Apr 2017 - Drug Updates

Multiple sclerosis: Rebound syndrome after stopping fingolimod (Gilenya▼) or switching therapy

HCPs advised to report adverse effects associated with fingolimod (Gilenya▼) or other treatments for multiple sclerosis.

  • 28 Jul 2017 - Drug Updates

Bendamustine (Levact): Increased mortality when used in combination treatment outside the approved indications

Closely monitor patients for opportunistic infections as well as cardiac, neurological, and respiratory adverse events.

  • 19 Jul 2016 - Drug Updates

Suspected fatal drug interaction between citalopram and cocaine

Prescribers should consider possible illicit drug use when prescribing medicines with potential for interactions

  • 19 Jul 2016 - Drug Updates

Rare reports of calciphylaxis in patients taking warfarin

Warfarin linked to cases of calciphylaxis, a very rare but serious condition

  • 19 Apr 2016 - Drug Updates

Drug safety alert: Minimizing cardiac side effects associated with concomitant use of apomorphine and domperidone

Patients receiving apomorphine and domperidone require cardiac risk assessment and ECG monitoring to reduce the risk of serious arrhythmia related to QT-prolongation

  • 19 Apr 2016 - Drug Updates

Drug safety update: Risk of progressive multifocal leukoencephalopathy with dimethyl fumarate (Tecfidera)

Reports of progressive multifocal leukoencephalopathy in patients receiving dimethyl fumarate for multiple sclerosis, who all had prolonged lymphopenia

  • 19 Apr 2016 - Drug Updates

Drug safety alert: Risks of PML, basal-cell carcinoma, and opportunistic infections associated with Fingolimod (Gilenya▼)

Fingolimod can increase the risk of progressive multifocal leukoencephalopathy and opportunistic infections owing to its immunomodulatory effects.