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LDL-C Reduction after Acute Coronary Syndrome: How to reconcile practice with current guidelines?

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LDL-C Reduction after Acute Coronary Syndrome: How to reconcile practice with current guidelines?

Prof. François Schiele
CHU de Besançon, Service de Cardiologie, Université de Franche Comté
 
 

Patients admitted for an Acute Coronary Syndrome must be treated with high intensity statins, as early as possible and irrespective of the LDL-C level. LDL-C level at admission is helpful to guide treatment intensity, in order to reach the target LDL-C below 70mg/dL, ideally, 55mg/dL. The addition of ezetimibe, on top of statins, might be necessary to reach the LDL-C target, according to the LDL-C at admission. Scientific rationale and modalities of lipid lowering treatment before discharge are discussed.