Do not use Solu-Medrone 40 mg in patients with a known or suspected allergy to cows’ milk

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Methylprednisolone, a corticosteroid indicated for treatment of wide variety of indications including allergic states, dermatological disease, and gastrointestinal diseases. Solu-Medrone 40 mg uses lactose produced from cows’ milk as an excipient and contain trace amounts of milk proteins; while other strengths of Solu-Medrone do not contain lactose.
 

Cows’ milk allergy is an adverse reaction of an immunological nature induced by cows’ milk proteins. Estimates of prevalence of cows’ milk allergy based on food challenge vary from 0% to 3%. Most children outgrow their allergy in early childhood and only a small proportion of patients remain allergic in adulthood. Cows’ milk allergy should be clearly distinguished from lactose intolerance, which is a non-immunologically mediated reaction to milk caused by a lack of the enzyme lactase in the small intestine, which breaks lactose from milk down into glucose and galactose.
 

A recent EU review reported cases of allergic reactions, including bronchospasm and anaphylaxis, in patients ...

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Do not use Solu-Medrone 40 mg in patients with a known or suspected allergy to cows’ milk

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