AACR 2019—​​​​​​​HPV vaccination rates low in adults at high risk for HIV


  • Univadis
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Takeaway

  • Young adults at high risk for HIV are undervaccinated for HPV.

Why this matters

  • HIV/HPV coinfection increases risk of anal, cervical, and oropharyngeal cancer (incidence ratios in HIV vs general US population: 9.2, 2.9, and 2.7, respectively), many of which are HPV vaccine-preventable.

Study design

  • Retrospective, descriptive analysis of data from 416 age-eligible respondents to the 2016 Behavioral Risk Factor Surveillance System (BRFSS) survey with behavioral risk factors for HIV.
  • Because HPV vaccine was licensed for use in females in June 2006 and males in 2010, and recommended dosing strategies have changed over time, outcomes were defined as unvaccinated (0 doses), initiated vaccination (1-2 doses), and completed vaccination (3 doses), and the analysis included:
    • Females 18-36 years.
    • Heterosexual males 18-28 years.
    • Gay or bisexual males 18-33 years.
  • Funding: NIH.

Key results

  • Among populations at behaviorally high risk for HIV, proportions who initiated/completed vaccination were:
    • 25.7%/6.3%, respectively, of gay/bisexual males.
    • 4.8%/25%, respectively, of heterosexual females.
    • 8.1%/2.8%, respectively, of heterosexual males.
  • Overall vaccination rates were lower in black and Hispanic vs white populations: 4.9%, 8.2%, and 14.7% had completed vaccination in each group, respectively.
  • No transgender respondents had completed or initiated vaccination.

Limitations

  • Retrospective; findings not generalizable to general US population.

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