Acne is linked to depression and anxiety risk: meta-analysis

  • Samuels DV & al.
  • J Am Acad Dermatol
  • 20 Feb 2020

  • curated by Brian Richardson, PhD
  • Clinical Essentials
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Takeaway

  • Patients with acne vulgaris are at increased risk for depression and anxiety, according to a systematic review and meta-analysis.

Why this matters

  • This is the first quantitative review on the association between acne vulgaris and depression/anxiety.

Key results

  • Acne vulgaris was associated with both depression and anxiety (P<.00001 for both>
  • The link to depression was stronger in adults vs adolescents (P=.016), as was the link to anxiety (P=.041).

Study design

  • 42 studies were included in the meta-analysis (1,029,299 participants from 35 studies in the depression analysis; 21,634 participants from 24 studies in the anxiety analysis).
  • Funding: None.

Limitations

  • Heterogeneity between included studies.