Acute ischaemic stroke: can sleep apnoea predict functional outcomes?

  • Nair R & al.
  • J Stroke Cerebrovasc Dis
  • 14 Dec 2018

  • curated by Antara Ghosh
  • UK Clinical Digest
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Takeaway

  • Sleep apnoea is independently associated with increased risk for acute ischaemic stroke and poor functional outcome.
  • An association was also observed between sleep apnoea and other known stroke risk factors like hypertension.

Why this matters

  • Considering sleep apnoea in patients with acute ischaemic stroke could improve chances of recovery and reduce the risk for recurrence.

Study design

  • This prospective observational study evaluated 102 consecutive patients with acute ischaemic stroke with hemiplegic upper limb.
  • Sleep disordered Questionnaire, Berlin Questionnaire and Epworth sleepiness scale assessed sleep apnoea.
  • Functional outcome was measured using Barthel score.
  • Funding: None disclosed.

Key results

  • 31 (30.3%) patients had sleep apnoea.
  • Presence of hypertension was more in the apnoea vs no apnoea group (64.5% vs 43.6%; P=.052).
  • Gain in mean Barthel score at the end of 3 months showed significant improvement in patients with no sleep apnoea (P<.001 suggesting an association between sleep apnoea and increased risk for ischaemic stroke.>

Limitations

  • Single-center study.
  • Polysomnography not done to establish the diagnosis of sleep apnoea.