- EASE, a novel psychological and palliative care intervention, demonstrated feasibility and efficacy in improving physical and psychological well-being in patients with newly diagnosed acute leukemia (AL).
Why this matters
- Similar interventions have reduced psychological distress and improved quality of life in patients with solid tumors.
- Phase 2 study to compare usual care (UC) alone (n=20) vs UC+Emotion and Symptom-Focused Engagement (EASE; n=22), a novel psychotherapeutic intervention, in 42 patients with newly diagnosed AL.
- Funding: Canadian Cancer Society Research Institute; Princess Margaret Cancer Centre, Princess Margaret Cancer Foundation; University Health Network, Toronto, Ontario, Canada; Ontario Ministry of Health and Long-term Care.
- All predefined feasibility endpoints were met.
- EASE delivered significant reductions in outcomes including the following (P<.05 for each vs baseline style="list-style-type:circle;">
- Pain interference at 4 and 12 weeks.
- Clinically relevant symptoms of acute stress disorder (ASD)/threshold ASD.
- Significant worsening of pain interference (P<.05>
- Significant decrease in satisfaction with care (P<.05>
- Limited sample size.