- Survivors of acute respiratory distress syndrome (ARDS) experience worse physical decline after hospital readmissions that include an ICU stay vs readmissions that do not.
Why this matters
- ARDS survivors often suffer long-term health problems and hospital readmissions.
- 64% (n=84) experienced ≥1 readmission. Of those:
- 42% (n=35) had ≥1 ICU stay;
- 54% (n=45) had readmissions across multiple years.
- On multivariate analysis, rate of physical decline did not differ after readmission without an ICU stay vs no readmission.
- However, decline worsened after readmission with ICU stay vs no readmission (ORs):
- Strength: 2.59 (P=.01);
- Exercise capacity: 4.99 (P<.001>
- Self-reported physical function: 8.85 (P<.001>
- Strength: 2.32 (P=.06);
- Exercise capacity: 3.00 (P=.03);
- Self-reported function: 4.09 (P=.001).
- Multisite, 5-year, longitudinal prospective cohort study.
- Participants: 132 adults who had survived >2 years after ARDS.
- At years 3, 4, and 5, researchers assessed outcomes in those readmitted to hospital and with vs without ICU stay.
- Outcome: rate of physical decline or death.
- Funding: NIH; Johns Hopkins Institute for Clinical and Translational Research.
- Small study.
- Study took place before hospitals adopted early-mobilization policies.