- Despite ongoing, consistent clinical exposure, SARS-CoV-2 seroprevalence is low among Belgian health care professionals except among those living with someone with suspected COVID-19.
Why this matters
- Personal protective equipment, high infection control standards, and regular screening in hospital staff, together with contact tracing and quarantine, were associated with low seroprevalence.
- 74% (3056/4125) of staff participated.
- Overall, 6.4% (197; 95% CI, 5.5%-7.3%) had SARS-CoV-2 antibodies.
- Age did not affect antibody status:
- With antibodies, mean age was 39.5 (standard deviation, 13.1) years.
- Without antibodies, it was 41.3 (12.4) years.
- Sex also did not affect antibody status.
- ORs (95% CIs) for seropositivity:
- With suspected COVID-19+ household contact: 3.15 (P<.001>
- Any patient contact: 0.91 (0.67-1.25).
- Working during lockdown: 1.14 (0.59-2.57).
- Contact with patient who had COVID-19: 1.08 (0.80-1.45).
- Contact with colleague who had COVID-19: 1.03 (0.77-1.38).
- 75% (2294/3052) of staff reported 1 prior symptom.
- 15% (30/197) of staff with antibodies reported no symptoms.
- Antibodies were associated (ORs; 95% CIs) with prior:
- Anosmia: 7.78 (5.22-11.53).
- Fever: 2.23 (1.49-3.31).
- Cough: 1.44 (1.00-2.07).
- Prospective case screening analysis of prevalence of antibodies against SARS-CoV-2 among Belgian hospital staff, April 22-30, 2020.
- Funding: None disclosed.
- ~26% of staff untested.