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Clinical Summary

Are dairy products linked to acne?

Takeaway

  • Meta-analysis suggests that intake of any dairy products such as milk, full-fat dairy, whole milk, low-fat/skim milk and yogurt were associated with a higher odds ratio for acne compared with no intake in children, adolescents, and young adults.
  • Authors advise caution while interpreting results because of heterogeneity and bias across studies.

Why this matters

  • Association between high acne prevalence rates in western countries and dairy and processed food consumption is often debated.
  • Moderating dairy content in the diet may help individuals with acne.

Study design

  • Meta-analysis of 14 studies including 78,529 individuals aged 7-30 years (23,046 acne-cases and 55,483 control individuals) published until December 2017.
  • Funding: None disclosed.

Key results

  • Compared with no intake, risk for acne was significantly higher for:
    • any dairy (OR, 1.25; P=6.13×10−8),
    • full-fat dairy (OR, 1.22; P=1.62×10−3),
    • any milk (OR, 1.28; P=8.23×10−5),
    • whole milk (OR, 1.22; P=6.66×10−3),
    • low-fat/skim milk (OR, 1.32; P=4.33×10−5),
    • cheese (OR, 1.22; P=5.21×10−2) and
    • yoghurt (OR, 1.36; P=2.21×10−2).
  • Compared with less than weekly frequency of any milk intake, the risk for acne was significantly higher with ≥2 glasses/day (OR, 1.43; 95% CI, 1.09-1.88) and 1 glass/day (OR, 1.41; 95% CI, 1.05-1.90).

Limitations

  • All studies were observational.
  • High heterogeneity.

References


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