Atopic dermatitis: patients' experience of pain varies

  • Silverberg JI & al.
  • J Allergy Clin Immunol Pract
  • 19 Jun 2019

  • International Clinical Digest
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Takeaway

  • Pain affects >60% of patients with atopic dermatitis (AD) and is associated with scratching, fissures, and inflamed skin.

Why this matters

  • Little is known about the prevalence and effect of pain in adults AD.

Key results

  • 61% of patients reported pain from AD/eczema.
    • 33% experienced pain at least once per week.
    • 5% experienced daily pain.
    • Prevalence of pain decreased with age (P=.0008).
  • Among patients reporting pain from AD, 48% reported pain "only after scratching a lot," 42% reported pain that "comes and goes throughout the day," and 11% reported pain "constantly throughout the day."
  • Pain from AD was most commonly associated with open areas caused by scratching (27%), small cracks in the skin (27%), inflamed red skin (25%), and burning from creams/ointments (10%).
  • Patients with face lesions had lower proportions of pain "only after scratching a lot" (P=.02).
  • Patients with back lesions had fewer reports of "pain from open areas by scratching" (P=.01).

Study design

  • 602 adults with AD were analyzed for pain characteristics and associations.
  • Funding: Sanofi Genzyme; Regeneron.

Limitations

  • Self-reported data from internet survey.