- Pain affects >60% of patients with atopic dermatitis (AD) and is associated with scratching, fissures, and inflamed skin.
Why this matters
- Little is known about the prevalence and effect of pain in adults AD.
- 61% of patients reported pain from AD/eczema.
- 33% experienced pain at least once per week.
- 5% experienced daily pain.
- Prevalence of pain decreased with age (P=.0008).
- Among patients reporting pain from AD, 48% reported pain "only after scratching a lot," 42% reported pain that "comes and goes throughout the day," and 11% reported pain "constantly throughout the day."
- Pain from AD was most commonly associated with open areas caused by scratching (27%), small cracks in the skin (27%), inflamed red skin (25%), and burning from creams/ointments (10%).
- Patients with face lesions had lower proportions of pain "only after scratching a lot" (P=.02).
- Patients with back lesions had fewer reports of "pain from open areas by scratching" (P=.01).
- 602 adults with AD were analyzed for pain characteristics and associations.
- Funding: Sanofi Genzyme; Regeneron.
- Self-reported data from internet survey.