- Increasing severity of atopic dermatitis is associated with cognitive dysfunction in adults, according to a prospective, questionnaire-based study.
Why this matters
- The relationship between atopic dermatitis severity and cognitive function is poorly understood.
- 12.4% of patients had mild cognitive dysfunction, 5.4% had moderate cognitive dysfunction, and 5.2% had severe dysfunction.
- Increased atopic dermatitis severity was associated with decreased cognitive function.
- Significant outcomes (P<.05 were found for patient-reported global atopic dermatitis numerical rating scale worst-itch patient oriented eczema measure scoring dermatitis-sleep poem-sleep and nrs skin-pain.>
- Cognitive function was inversely associated with Dermatology Life Quality Index (P=.002) and Itchy Quality of Life (P<.0001 scores.>
- 386 adult patients with atopic dermatitis were evaluated for cognitive function by the Patient-Reported Outcomes Measurement Information System Cognitive Function 8-item short form.
- Funding: Agency for Healthcare Research and Quality; Dermatology Foundation; Galderma, LLC.
- Self-reported data.
- Uncontrolled single-center study.