- Electrochemotherapy (ECT) is associated with a similar recurrence rate as surgery in patients with basal cell carcinoma, according to a randomized controlled trial.
Why this matters
- ECT appears to represent a viable alternative for patients with BCC.
- ECT was associated with a 100% response rate (12% of patients needed a second treatment to ensure complete response).
- Surgery was associated with a 100% complete excision rate on histology (5% of patients needed a second excision).
- Surgery and ECT were associated with similar recurrence rates (1.9% vs 7.5%; P=.33) in intention-to-treat analysis.
- 100 patients with BCC were randomly assigned: 52 to ECT and 48 to surgery.
- 87 patients, 45 treated with ECT and 42 treated with surgery, were treated and followed up at 6 months.
- Funding: Breakthrough Cancer Research.
- Small patient sample size.