Breast cancer: 93% of survivors report persistent health issues

  • de Ligt KM & al.
  • Breast
  • 4 Apr 2019

  • International Clinical Digest
Access to the full content of this site is available only to registered healthcare professionals. Access to the full content of this site is available only to registered healthcare professionals.

Takeaway

  • A Dutch cohort study finds that 93% of patients with early breast cancer (eBCa) report symptoms up to 5 years postdiagnosis.
  • More than 50% report various health problems regarding the breast, and/or musculoskeletal, central nervous system (CNS), and reproductive system.

Why this matters

  • Patients should be informed about long-term health problems years after treatment.
  • Clinicians should perform better treatment planning.

Study design

  • Cross-sectional cohort of 876 women with eBCa (2012-2016) who were contacted up to 5 years postdiagnosis in 20 Dutch hospitals; 404 responded electronically.
  • Funding: None.

Key results

  • Median age, 62.0 years.
  • In addition to breast surgery, patients were treated with radiotherapy (72%), chemotherapy (49%), endocrine therapy (57%), and axillary dissection (21%).
  • 93% of patients reported 1 or more health problems.
  • >50% experienced fatigue, psychological problems, and health problems in the breast, and/or musculoskeletal, CNS, and reproductive system.
  • Chemotherapy was associated (P<.05 with increased risk for fatigue p=".020)," respiratory gastrointestinal cns and skin problems>
  • 64% of the respondents were using some type of healthcare for at least 1 of the problems, most commonly for fracture (78.6%) and gastric/abdominal complaints (51.0%).

Limitations

  • Moderate response rate.
  • Lack of control group.

Please confirm your acceptance

To gain full access to GPnotebook please confirm:

By submitting here you confirm that you have accepted Terms of Use and Privacy Policy of GPnotebook.

Submit