Catheter ablation for ventricular tachycardia bests non-ablative approaches | J Interv Card Electrophysiol

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  • Meta-analysis results of three trials show odds of ventricular tachycardia (VT) recurrence are 53% reduced with ablation vs non-ablation therapies in patients with ischemic heart disease. 

Key results

  • Three trials, 262 patients had ablation (n=129) or non-ablative interventions (beta-blockers±antiarrhythmics) (n=133). 
  • Cumulative OR for recurrent VT, 0.471 (95% CI, 0.176–1.257) for ablation vs non-ablative therapies.
  • Cumulative OR for death, 0.766 (95% CI, 0.351–1.674). 

Study design

  • Meta-analysis, RCTs. 

Why this matters

  • Catheter ablation may be better than non-ablative strategies at preventing implantable cardioverter defibrillator shocks for ventricular arrhythmias.