- About 17% of patients with lung cancer who underwent surgical resection developed chronic postsurgical pain (CPSP) within 36 months of surgery, and more than one-third of this group are prescribed strong opioids for pain.
Why this matters
- Few data address the incidence of long-term delayed or recurrent CPSP, which can contribute to functional disability, poor QoL, and chronic opioid use.
- 3200 patients underwent thoracic surgery for lung cancer.
- Funding: None.
- 17.4% were diagnosed with CPSP within 36 months of surgery.
- New CPSP diagnoses in 14.3% at 3 months after surgery and 3.1% at ≥6 months.
- Incidence of CPSP decreased during the study period.
- 85.1% with CPSP received analgesics, 36.9% of whom received strong opioids, and 17.0% of whom received strong opioids for >90 days after surgery.
- Independent predictors (HRs) of CPSP within 36 months of surgery included:
- Female sex: 1.20 (P=.05).
- Longer surgery duration: 1.11 (P<.01>
- Postoperative chemotherapy: 1.55 (P<.001>
- Postoperative radiation therapy: 1.35 (P=.02).
- Retrospective, single-center study.