Cochrane review: gabapentin is not effective in ALS

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Takeaway

  • Gabapentin did not improve survival or slow disease progression when compared with placebo in amyotrophic lateral sclerosis (ALS).

Why this matters

  • Gamma aminobutyric acid (GABA) imbalance may play a role in the pathogenesis of ALS.

Key results

  • Only 2 trials met inclus...