A new study suggests that coffee consumption does not have a significant association with the overall risk for cancer diagnosis or cancer death.
Researchers conducted a Mendelian randomisation study using 46,155 cases of cancer (6998 fatalities) and 270,342 control individuals of white British ancestry from the UK Biobank cohort.
No observational association was evident between coffee intake and the overall risk for cancer [OR for one cup/day increase, 0.99, 95% CI, 0.98-1.00] or cancer death (OR, 1.01, 95% CI, 0.99-1.03). The associations between coffee consumption and risks for individual cancer were consistent with a null effect, with little or no association between most cancers and coffee intake (average OR for one cup/day increase, ~0.98).
Writing in the International Journal of Epidemiology, the authors said their heterogenous "approach captures whether a change in coffee consumption has a ‘net-effect’ on modifying cancer risk/mortality in a population, assuming that the distribution of cancers is similar to those sampled in the UK Biobank cohort."
