Cognitive decline linked to low serum TSH

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  • Among nondemented elderly, low-normal serum thyroid stimulating hormone (TSH; <1.0 μIU/mL) was linked to cognitive decline.

Study design

  • Cross-sectional analysis of 293 healthy adults aged 65 y or older with normal TSH identified nondemented adults for follow-up (median, 16 mo): 95 with TSH ≥1.0 μIU/mL; 8 with TSH <1.0μIU/mL, untreated; and 7 with TSH <1.0 μIU/mL treated with methimazole.
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