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Findings of the first large systematic review were inconclusive regarding the link between cognitive decline and oral health.
PubMed/Medline/CINAHL search identiﬁed 1,412 articles related to older adults between January 1993 and March 2013, of which 56 met eligibility criteria (40 cross-sectional; 16 longitudinal).
11 longitudinal studies examined the effect of oral health (number of teeth, periodontal disease, caries, denture use) on risk of cognitive decline/dementia on the basis of Mini-Mental State Examination or diagnosis, and the other 5 studies examined the reverse.
In some but not all studies, oral health measures were associated with the risk of cognitive decline or incident dementia.