Conception within 12 months of stillbirth does not affect birth outcomes

  • Regan AK & al.
  • Lancet
  • 28 Feb 2019

  • curated by Sarfaroj Khan
  • UK Clinical Digest
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Takeaway

  • Conception within 12 months of stillbirth is common and is not associated with increased risk for stillbirth, preterm birth, or small-for-gestational-age birth in the next pregnancy compared with a 2-year interval.

Why this matters

  • Findings could be used when counselling families that are planning future pregnancies after a stillbirth and provide reassurance to women who wish to become pregnant or unexpectedly become pregnant shortly after a stillbirth.

Study design

  • This international cohort study identified 14,452 births in women whose previous pregnancy had ended in stillbirth.
  • Interpregnancy interval was defined as the time between the end of pregnancy and the start of the next pregnancy.
  • Funding: National Health and Medical Research Council.

Key results

  • The median interpregnancy interval after a stillbirth was 9 months (interquartile range, 4-19); 9109 (63%) women conceived within 12 months and 5393 (37%) conceived within 6 months.
  • Of 14,452 births, 2% were stillbirths, 18% preterm births and 9% were small-for-gestational-age births.
  • Interpregnancy intervals of
  • Subsequent stillbirth (adjusted OR [aOR], 1.09; 95% CI, 0.63-1.91 for
  • Preterm birth (aOR, 0.91; 95% CI, 0.75-1.11 for
  • Small-for-gestational-age birth (aOR, 0.66; 95% CI, 0.51-0.85 for

Limitations

  • Findings might not be generalisable to low- or middle-income and countries without access to universal health care or ethnic minority groups.

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