- Former football players with concussion symptoms during their career were more commonly recommended or prescribed testosterone or medications for erectile dysfunction (ED).
Why this matters
- Long-term potential for pituitary insufficiencies and related problems among individuals experiencing head trauma.
- Prevalence of indicators:
- Low testosterone indicator: 18.3%.
- ED indicator: 22.7%.
- In adjusted models, higher concussion symptom score was associated with increased odds of:
- Low testosterone indicator (highest vs lowest quartile, OR, 2.39; P<.001>
- ED indicator (highest vs lowest quartile, OR, 1.72; P<.001>
- Men ≤50 years of age.
- Men who last played ≥20 years before study.
- Cross-sectional cohort study of 3409 former professional football players (mean age, 52.5 years).
- 10-item concussion symptoms score (e.g., loss of consciousness, disorientation, nausea, memory problems, dizziness at time of football-related head injury).
- Main outcomes: self-reported recommendation or prescription for low testosterone, for ED medication.
- Funding: Sidney R. Baer, Jr. Foundation; National Institutes of Health; others.
- Indicators were indirect measures.
- Retrospective collection of concussion data.
- Symptom scale has not been validated.
- Temporal association unknown.