- Among inpatients with COVID-19 in Wuhan, China, deep venous thrombosis (DVT) was common, according to results of this single-center study.
Why this matters
- COVID-19 has been associated with hypercoagulability in many patients with severe infection and lung injury.
- 37.1% received low-molecular-weight heparin thromboprophylaxis (similar rates in those with vs without DVT).
- 74.1% were severely or critically ill.
- DVT prevalence: 46.1% (66/143 patients).
- Among subgroup with Padua score ≥4 who underwent ultrasound >72 hours after admission:
- Heparin nonprophylaxis vs prophylaxis: 66.0% vs 36.7% (P=.010).
- DVT vs no DVT:
- ICU admission: 12 vs 3 (P=.005).
- Discharges: 32 vs 60 (P<.001>
- Deaths: 23 vs 9 (P=.001).
- Single-center observational study of 159 consecutive patients hospitalized with COVID-19 in Wuhan, China (n=143).
- All underwent leg ultrasound, echocardiography, except 16 who died or were transferred.
- Outcomes: DVT prevalence, risk factors, prognosis.
- Funding: National Natural Science Foundation of China.
- Patients had waited a long time for admission because of crowding.
- Scant data on thromboprophylaxis.
- Pulmonary embolism prevalence not determined.
- No control group.