CRC: ERAS program beneficial after laparoscopic surgery

  • Ni X & al.
  • J Gastrointest Surg
  • 11 Mar 2019

  • curated by Jim Kling
  • Univadis Clinical Summaries
Access to the full content of this site is available only to registered healthcare professionals. Access to the full content of this site is available only to registered healthcare professionals.

Takeaway

  • A meta-analysis reveals that enhanced recovery after surgery (ERAS) led to fewer complications and shorter hospital stays in patients undergoing laparoscopy for colorectal cancer.
  • There was no significant difference in 30-day readmission rates or mortality.
  • The multimodal program uses 17 items in an effort to reduce surgery stress, accelerate functional recovery, and reduce postoperative morbidity.

Why this matters

  • Existing trials of ERAS in colorectal cancer have yielded mixed results, and previous meta-analyses relied on fewer and lower-quality trials.

Study design

  • Meta-analysis of 13 studies (n=1298) conducted in China, Korea, the Netherlands, Italy, and Egypt.
  • Funding: None disclosed.

Key results

  • Compared with traditional care (TC), ERAS was associated with a shorter postoperative hospital stay (weighted mean difference [WMD], −2.00 days; P=.00; 12 studies).
  • ERAS was associated with a shorter time to first flatus (WMD, −12.18 hours; P=.00; 9 studies) and time to first defecation (WMD, −32.93 hours; P=.00; 7 studies).
  • 17.84% of ERAS patients experienced postoperative complications compared with 27.01% of TC (risk ratio, 0.59; P<.01 studies>
  • There was no significant difference in 30-day readmission rates or mortality rates (5 studies).

Limitations

  • Significant heterogeneity in some analyses.

Please confirm your acceptance

To gain full access to GPnotebook please confirm:

By submitting here you confirm that you have accepted Terms of Use and Privacy Policy of GPnotebook.

Submit