- Synchronous hepatic and colorectal resection in patients with colorectal cancer (CRC) is associated with a higher rate of major complications compared with liver-only resection, but a similar rate of liver complications and mortality.
Why this matters
- The patient profiles between the 2 groups were similar, suggesting that it may be possible to identify patients at greater risk of complication during synchronous procedures.
- Retrospective analysis of 1138 hepatic resections due to CRC metastases from the NSQIP database (98 synchronous liver and colon, 1040 liver resection alone).
- Funding: None disclosed.
- Overall 30-day mortality rate:
- Overall, 1.1%;
- Synchronous, 3.1%;
- Liver-only, 0.9%; P=.077.
- There was no significant difference between synchronous and liver-only in the frequency of liver failure (3.3% vs 4.1%; P=.722) or biliary leak (5.3% vs 9.6%; P=.084).
- The synchronous group had higher rates of surgical site infection (14.3% vs 5.6%; P=.001), sepsis (9.2% vs 3.9%; P=.016), length of hospital stay (9.39 vs 6.26 days; P<.001 repeat operation vs p=".017)," and need for postoperative intervention a complication>
- The synchronous group had a greater probability of experiencing a major complication (OR, 2.5; P<.001>
- Retrospective analysis.