Crohn Disease

  • Aaron E. Walfish Rafael Antonio Ching Companioni, Clinical Assistant Professor , Mount Sinai Medical Center Icahn School of Medicine, Elmhurst Hospital Center

  • MSD Manual
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  • Crohn disease is a chronic transmural inflammatory bowel disease that usually affects the distal ileum and colon but may occur in any part of the GI tract. Symptoms include diarrhea and abdominal pain. Abscesses, internal and external fistulas, and bowel obstruction may arise. Extraintestinal symptoms, particularly arthritis, may occur. Diagnosis is by colonoscopy and imaging studies. Treatment is with 5-aminosalicylic acid, corticosteroids, immunomodulators, anticytokines, antibiotics, and often surgery.

    (See also Overview of Inflammatory Bowel Disease.)

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  • Last modified in -By Aaron E. Walfish
    Last review 04-2019