- Trajectories of cardiovascular (CV) risk over time can be indicative of incident cardiovascular disease (CVD), according to findings from this population-based study in China.
- The authors characterize 5 trajectories, from lowest (highest CVD incidence) to highest (lowest CVD incidence).
Why this matters
- Cardiovascular health score may be a journey, not a single stop to measure along the way.
- Score incorporated smoking, body weight, physical activity, diet, plasma glucose level, plasma cholesterol level, and BP.
- 5 trajectories identified on 14-point max scale:
- Low-stable: 4.6-5.2 points.
- Moderate-increasing: mean increase from 5.4 to 7.8.
- Moderate-decreasing: mean decrease from 7.4 to 6.3.
- High-stable I: 8.8-9.0 points.
- High-stable II: 10.9-11.0 points.
- During 5 years, vs low-stable, high-stable II was linked to reduced risk for incident CVD:
- Adjusted HR, 0.21 (95% CI, 0.16-0.26).
- Association was stronger with younger age (vs age 60+ years).
- Prospective, population-based study of 74,701 adults (mean baseline age, 49.6 years) without CVD diagnoses.
- Funding: CyberScience Seed Grant Program, Pennsylvania State University.
- Included only Chinese adults from a single region, so generalizability is not known.