Diabetes: short-term intensive metabolic intervention achieves sustained drug-free remission

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Findings from a new trial suggest an intensive metabolic strategy delivered over two to four months may induce remission of type 2 diabetes (T2D).

For the study, published in the Journal of Clinical Endocrinology & Metabolism, 83 individuals with T2D were randomised to an eight-week or 16-week intensive metabolic intervention, or standard diabetes care. The metabolic intervention included a personalised exercise and meal plan that reduced calorie intake by 500-750 per day. These study participants met regularly with a nurse and dietitian to track their progress, and received oral medications and insulin at bedtime. Diabetes drugs were then discontinued in the intervention groups and participants were followed for hyperglycaemic re...