Diagnosing airflow obstruction: bronchodilator FVC response is more relevant than FEV1

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Takeaway
  • Post-bronchodilator (BD) change (∆) in FEV1% of baseline increased with increasing airflow obstruction, but ∆FEV1 z-scores or % predicted decreased with severe obstruction. ∆FVC increased with increasing impairment.

Why this matters

  • Recommendations on interpreting tests of BD...