- The benefits of dietary interventions for IBD remain uncertain, say the authors of this Cochrane review.
- 5 trials involving almost 500 people are underway, and results should help clarify the evidence.
Why this matters
- Diet affects disease activity in IBD, but evidence of benefit from specific dietary interventions is sparse.
- 18 randomized controlled trials included: 6 for active Crohn’s disease (CD); 7 for inactive CD; 1 for active ulcerative colitis (UC); 4 for inactive UC.
- Interventions focused on low or no consumption of specific triggering foods or on high fiber.
- Heterogeneity of interventions and controls precluded data pooling.
- Cochrane authors say that most studies lacked sufficient power, 14 had high bias risk.
- Some studies had tiny populations (e.g., 3 controls).
- Symptoms-guided diet seemed to have most robust results suggesting benefit.
- Relapses were common, often similar to control condition.
- No studies reported side effects.
- Cochrane review, 18 studies, 1878 participants.
- Funding: None, or other.
- The considerable limitations of the included studies.