- High levels of dietary magnesium intake were associated with a reduced risk for depression vs lower levels, even after adjusting for potential confounders, but the decrease was significant only in women.
Why this matters
- This is the first study to examine the dose-response relationship between dietary magnesium and depression risk.
- The association between dietary magnesium intake and risk for depression was evaluated in this study (n=17,730).
- Data were used from the National Health and Nutrition Examination Survey (2007-2014).
- Funding: None.
- High levels of dietary magnesium intake were inversely associated with risk for depression (P-trend <.001 style="list-style-type:circle;">
- crude: OR, 0.33 (95% CI, 0.26-0.42); and
- adjusted: OR, 0.47 (95% CI, 0.34-0.66).
- Cross-sectional study design.
Coauthored with Chitra Ravi, MPharm