- Most women diagnosed with diabetes prior to 24 gestational weeks had gestational diabetes mellitus (GDM) that resolved after delivery.
- HbA1c was superior to oral glucose tolerance testing in distinguishing undiagnosed pregestational diabetes from GDM at
- Definitive diagnosis should be done after delivery.
Why this matters
- Pregnancies complicated by pregestational diabetes are associated with more foetal and maternal complications than are GDM pregnancies.
- Population-based retrospective cohort study of 285 women with diabetes diagnosed during pregnancy at
- Funding: None.
- 11 (5%) women were diagnosed with diabetes within 6-12 weeks postdelivery.
- The most accurate marker for type 2 diabetes (T2D) was HbA1c, with a cutoff of 5.8% predicting T2D with:
- 89% sensitivity,
- 86% specificity,
- 99.4% negative predictive value (NPV), and
- 23% positive predictive value (PPV).
- A cutoff of 6.5% predicted T2D with:
- 56% sensitivity,
- 98.5% specificity,
- 98% NPV, and
- 62% PPV.
- Using HbA1c
- HbA1c was the only independent predictor for T2D: OR, 19 (95% CI, 3.2-109).
- Retrospective design.
- T2D evaluated after pregnancy.