Diverticulitis outcomes worse with ulcerative colitis vs Crohn's

  • Persaud A & al.
  • JGH Open
  • 1 Dec 2019

  • International Clinical Digest
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Takeaway

  • When treated for diverticulitis, patients with ulcerative colitis (UC) have worse hospitalisation outcomes than those with Crohn's disease (CD).
  • Outcomes for patients with CD are similar to those for patients with no IBD.

Why this matters

  • These findings may help clinicians recognise patients who may experience worse diverticulitis treatment outcomes or need a higher level of care.

Study design

  • Researchers analysed health information of patients admitted to hospitals with acute diverticulitis, comparing outcomes for those with preexisting CD, UC, or no IBD (N=1815; CD: n=1090 [mean age, 60±1.06 years; 57% women; 87% white]; UC: n=725 [mean age, 65±1.32 years; 67% women; 84% white]; no IBD: n=218,725 [mean age, 60.4±0.09 years; 58% women; 76.9% white]).
  • Primary outcomes: mortality, admission cost, length of stay (LOS), and colectomy.
  • Funding: None disclosed.

Key results

  • Patients with CD vs UC had lower:
    • Hospital costs: aOR, −14,537 (P=.03).
    • LOS: aOR, −1.31 (P=.02).
  • Patients with CD vs no IBD had no significant differences in:
    • Hospital costs: aOR, −2196 (P=.36).
    • LOS: aOR, 0.03 (P=.91).
    • Mortality: aOR, 2.47 (P=.22).

Limitations

  • Patient information was from an administrative database susceptible to coding inaccuracies and not designed to determine risk factors or causation.