- Diabetic ketoacidosis (DKA) increases mortality risk in older vs younger adults.
Why this matters
- Most DKA research has been in young people with type 1 diabetes, rather than in those older and/or with type 2 diabetes.
- Retrospective matched cohort study of 385 adults hospitalized with DKA between 2004 and 2017 at 1 Israeli medical center (
- Funding: None.
- The most common precipitating factors for those
- For ≥65 years, the most common triggers were infections (sepsis, pneumonia, urinary tract).
- Myocardial infarction and cerebrovascular accidents were more common precipitating factors for ≥65 years (7.7%) vs
- Serum glucose was higher in older patients (639 vs 539 mg/dL; P<.0001>
- In-hospital mortality was higher in older (16.7%) vs younger (1.6%) patients (P<.001 as were and mortality p>
- Hospital stays were longer in older (5 days) vs younger (3 days) patients (P<.001>
- In 1:1 analysis matched for sex and Charlson Comorbidity Index, older vs younger patients had higher in-hospital mortality (16.7% vs 0%; P=.001) and 30-day mortality (12.1% vs 1.5%; P=.016).
- Single institution.
- No analysis by diabetes, medication types.