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Lower urinary tract infection (LUTI) is associated with an increased risk for prostate cancer, especially in patients with repeated medical visits for LUTI.
Why this matters
Inflammation of the prostate caused by cystitis and urethritis may play a role in the etiology of prostate cancer.
Compared with the group without LUTI, risk of developing prostate cancer was significantly higher in both the cystitis cohort (adjusted HR=1.46) and urethritis cohort (adjusted HR=1.72).
Further analyses found that there was a significantly greater risk of developing prostate cancer in patients with 5 medical visits per year for cystitis (aHR=9.25) and urethritis (aHR=9.68) vs the non-LUTI cohort.