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Clinical Summary

Drop in IHD, stroke risk has not reached psychiatric patients

Takeaway

  • People with psychiatric diagnoses remain at elevated risk for ischaemic heart disease (IHD) and stroke compared with unaffected peers and despite overall absolute declines in rates of both.
  • Socioeconomic status appears to be a factor with some diagnoses, but not all.

Why this matters

  • The association of psychiatric diagnoses and stroke/IHD has been previously reported, but these authors examined whether the decreased rates overall had reached the psychiatric patient population.

Key results

  • IHD and stroke have both decreased over the years.
  • However, people with psychiatric disorders had increased risks ranging from 2- to 2.5-fold greater compared with their unaffected peers.
  • Socioeconomic status and sex were both factors in the age at which incidents occurred.
  • The sexes were not distinct in their relative risks for stroke and IHD with psychiatric disorders.
  • Lower socioeconomic status was tied to increasing risk, except for schizophrenia.

Study design

  • Scottish patient records covering 1991-2015.
  • The analysis covered:
    • 645,393 IHD and 276,073 stroke events among people without psychiatric hospital admissions.
    • 3180 IHD and 1433 stroke events among people with schizophrenia.
    • 4927 and 2600 events among those with bipolar disorder.
    • 11,260 and 5668 events among those with depression.
  • Funding: Wellcome Trust-University of Edinburgh Institutional Strategic Support Fund; others.

Limitations

  • Psychiatric diagnosis identification was based only on a related hospital admission, so generalisation to a less-affected population is unclear.
  • The emphasis on treatment during the covered period shifted from hospital to community care.

Curated and written by Emily J. Willingham, Ph.D.


References


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