Dual AUS-IPP implantation is safe for patients with neobladder

  • Loh-Doyle JC & al.
  • Urology
  • 18 Jan 2019

  • curated by Craig Hicks
  • Clinical Essentials
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Takeaway

  • Dual implantation of artificial urinary sphincter (AUS) and 3-piece inflatable penile prosthesis (IPP) can be performed safely in patients with neobladder without long-term risk for infection and reservoir-related complications.

Why this matters

  • Many patients with neobladder are affected both by erectile dysfunction (ED) and urinary incontinence (UI), despite the availability of excellent treatment options such as the AUS and IPP, say researchers.

Study design

  • Researchers analyzed the health records of patients who underwent radical cystectomy and neobladder followed by AUS and IPP implantation (n=39).
  • They compared perioperative data and postoperative outcomes with a those of matched group of patients without neobladder (n=48).
  • Funding: None.

Key results

  • Neobladder was not an independent risk factor for AUS revision, AUS erosion, AUS failure, IPP infection, or IPP failure.
  • Independent predictors of AUS infection for patients with dual implants included increasing age (OR, 1.32; P=.041) and diabetes (OR, 71.3; P=.035).
  • The odds of AUS failure increased with smoking history (OR, 6.27; P=.020) and previous pelvic radiotherapy (OR, 6.14; P=.038).

Limitations

  • The study was retrospective and single-center.

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