- Dysphagia is associated with significantly higher mortality risk among patients with lung cancer.
- Dysphagia was present at lung cancer diagnosis in 4% of patients in this study.
- It was more common in patients who had SCLC, were aged ≥75 years, were black or from rural areas, and had comorbidities or metastasis.
Why this matters
- Although dysphagia has been reported in as many as 68% of previous lung cancer studies, its effect on patients with lung cancer is largely unknown.
- 201,674 patients with lung cancer.
- Funding: National Institutes of Health.
- 61% had NSCLC, 14% SCLC, and 25% unspecified.
- 4% had dysphagia before lung cancer diagnosis.
- Dysphagia was more likely (ORs) for:
- Age 75-79 years: 1.16 (P≤.001).
- Age 80-84 years: 1.29 (P<.0001>
- Age ≥85 years: 1.44 (P<.0001>
- Black patients: 1.21 (P<.0004>
- Rural patients: 1.27 (P<.0001>
- With Charlson comorbidity score 1: 1.36 (P<.0001>
- With Charlson comorbidity score ≥2: 1.56 (P<.0001>
- Regional metastasis: 1.60 (P<.0001>
- Distant metastasis: 1.64 (P<.0001>
- SCLC: 1.32 (P<.0001>
- Retrospective study.