E1224 displays a transient suppressive effect on parasite DNA clearance


  • The Lancet Infectious Diseases
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Background

Chagas disease is a major neglected vector-borne disease. In this study, we investigated the safety and efficacy of three oral E1224 (a water-soluble ravuconazole prodrug) regimens and benznidazole versus placebo in adult chronic indeterminate Chagas disease.

Method

In this...